Jacques Genest received his medical degree from McGill University, where he also completed his residency in internal medicine. He then pursued postdoctoral training in cardiology at Tufts University in Boston, focusing on lipoprotein metabolism and molecular genetics.
Since 2000, he has been a Professor of Medicine at McGill University and holds the McGill/Novartis Chair in Medicine. From 2000 to 2010, he served as Chief of Cardiology at McGill University, and from 2010 to 2014, he was the Scientific Director of the Centre for Innovative Medicine at the McGill University Health Centre (MUHC).
His research focuses primarily on lipid metabolism, the genetic basis of premature coronary arteryThe two coronary arteries, the right and the left, form the blood network that supplies the heart with oxygen and nutrients. They are located directly on the surface of the heart and branch into smaller vessels that disease, and the role of high-density lipoproteins (HDL) in atherosclerosis. His team has contributed to the identification of several genes involved in HDL metabolism. His research is funded by the Canadian Institutes of Health Research and the Heart and Stroke Foundation of Canada.
He has been actively involved in numerous national and international clinical studies. He serves on advisory boards for several pharmaceutical and biotechnology companies and is a reviewer for numerous scientific journals and granting agencies.
He has authored over 320 peer-reviewed articles in leading journals such as Nature Genetics, Circulation, Circulation Research, New England Journal of Medicine, Journal of Biological Chemistry, and The Lancet, and has written 18 book chapters.
For nearly two decades, he has contributed to the development of Canadian guidelines for cholesterolCholesterol is essential for the proper functioning of the human body, but it can also have harmful effects if present in excess. >> management. He currently leads Familial Hypercholesterolemia Canada, a clinical network dedicated to optimizing care for patients with this condition. In 2013, he co-founded FHCanada (www.FHCanada.net), a national patient registry for familial hypercholesterolemia.