atorvastatine [Lipitor™], fluvastatine [Lescol™], lovastatine [Mevacor™], pravastatine [Pravachol™], rosuvastatine [Crestor™], simvastatine [Zocor™]
Statins are a well-known class of drugs whose names all end in “-vastatin,” making them easy to identify in a list of prescriptions.
Their actions
They work by blocking a key enzyme involved in the liver’s production of cholesterolCholesterol is essential for the proper functioning of the human body, but it can also have harmful effects if present in excess. >>. This mechanism effectively reduces bloodBlood is composed of red blood cells, white blood cells, platelets, and plasma. Red blood cells are responsible for transporting oxygen and carbon dioxide. White blood cells make up our immune defense system. Platelets contribute to blood cholesterolCholesterol is essential for the proper functioning of the human body, but it can also have harmful effects if present in excess. >> levels, particularly LDL cholesterolCholesterol is essential for the proper functioning of the human body, but it can also have harmful effects if present in excess. >> — commonly referred to as “bad cholesterolCholesterol is essential for the proper functioning of the human body, but it can also have harmful effects if present in excess. >>.”
Statins are used to:
- Provide primary prevention, reducing the risk of heart attacks or strokes in at-risk individuals, even if they’ve never experienced a cardiovascular event;
- Offer secondary prevention in patients who have already had a heart attack, stroke, or another cardiovascular disease, to help prevent recurrence.
Dosage
This treatment is usually taken once daily, often in the evening.
Side effects
The most commonly reported side effects are nausea, diarrhea, and headaches. These are typically mild and temporary.
In some cases, patients may experience muscle pain — if this occurs, it’s important to speak promptly with a doctor or pharmacist to determine whether the dosage should be adjusted or the treatment reassessed.
A reassuring safety record
Despite concerns sometimes spread online, statins have been extensively studied in clinical trials and monitored in real-world settings.
Millions of patients worldwide have been taking them for over 30 years, and their safety profile is well known and considered favorable by health authorities.
Their ability to reduce serious cardiovascular events is scientifically proven, and statins are viewed as a cornerstone of cardiovascular prevention.
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