Digitalis

Digoxin is a medication that has been used in cardiology for a long time. Derived from the digitalis plant, a medicinal plant known for centuries, it is part of the history of modern cardiology.

Read more: Digitalis in Medecine

Digitalis – Digoxin (Lanoxin™, Toloxin™)

It helps slow the heart rate and slightly increase the strength of heart muscle contraction.

It is mainly prescribed for certain people with heart rhythm disorders, such as atrial fibrillation or atrial flutter, as well as for those whose heart pumping function is reduced.

How does it work?

Digoxin works primarily by enhancing the action of the parasympathetic nervous system, also known as the rest-and-relaxation system. This part of the nervous system is naturally active when the body is calm and relaxed, and its effect is to slow the heart rate.

By strengthening this calming influence on the electrical system of the heart, digoxin slows the transmission of electrical signals between the atriaThe atria are the two upper chambers of the heart. They act as reservoirs for blood that will fill the ventricles. and the ventricles. As a result, the heart beats more slowly and more regularly.

This mechanism explains why digoxin is often more effective at rest, particularly in older adults. In contrast, in younger individuals or during physical activity, when the sympathetic nervous system (the system of action and acceleration) is dominant, its effect on slowing the heart rate may be less pronounced.

Digoxin also provides a modest increase in the strength of heart muscle contraction, which may improve pumping efficiency in some individuals.

How is it taken?

Digoxin is usually taken once daily, at a precise dose. This medication must be used carefully, as the difference between an effective dose and an excessive dose is relatively narrow. For this reason, it is important to strictly follow the medical prescription.

Expected benefits

When appropriately prescribed, digoxin may help achieve better control of the heart rate, reduce palpitations“Palpitation” is a symptom related to an abnormality in heartbeats. There are several types of arrhythmias. This term is like a surname that encompasses several first names., and, in some people, improve shortness of breath and exercise tolerance.

Monitoring and risk of toxicity

Digoxin requires regular medical follow-up, as excessive accumulation of the medication in the body can lead to digoxin toxicity.

This risk is higher in certain situations, particularly in cases of dehydration, impaired kidney function, or interactions with other medications.

The physician may order bloodBlood is composed of red blood cells, white blood cells, platelets, and plasma. Red blood cells are responsible for transporting oxygen and carbon dioxide. White blood cells make up our immune defense system. Platelets contribute to blood tests to measure digoxin levels and ensure they remain within a safe range, while also monitoring kidney function and other ongoing treatments.

Warning signs to watch for

The most common mild side effects are nausea and dizziness.

However, some symptoms may indicate toxicity and require prompt medical attention. These include severe or persistent nausea or vomiting, visual disturbances (blurred vision or the appearance of yellow halos), marked muscle weakness, unusual fatigue, or an excessively slow heart rate.

Important message

Digoxin remains a useful and effective medication in specific situations, but it requires careful dosing and close monitoring.

It is essential never to change the dose or stop the medication without medical advice, as both overdose and inappropriate discontinuation can have serious consequences.