Calcium Channel Blockers (CCBs)

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Calcium channel blockers are medications used to treat high blood pressure, certain arrhythmias, and angina.
They work by helping blood vessels widen and, depending on the type, by slowing the heart rate.

There are two main categories:

  • Those that act mainly on the heart,
  • And those that act mainly on the blood vessels.

1. Cardiac CCBs

Examples: diltiazem (Cardizem™, Tiazac XC™), verapamil (Isoptin™)

These medications slow the heartbeat and slightly lower blood pressure.
They are often prescribed to:

  • control certain arrhythmias (by slowing the heart rate),
  • relieve angina,
  • or lower blood pressure.

 

They are usually taken once a day.

Possible side effects: fatigue, dizziness, and sometimes constipation (more common with verapamil).

2. Vascular CCBs

Examples: amlodipine (Norvasc™), nifedipine (Adalat™), felodipine (Plendil™))

These medications act mainly on the blood vessels, helping them dilate and thereby reduce blood pressure.
They are used to:

  • treat hypertension,
  • or relieve symptoms of angina.

 

They are also usually taken once a day.

Possible side effects: dizziness and, in some people, swelling of the feet or ankles.