{"id":17857,"date":"2026-05-20T17:50:31","date_gmt":"2026-05-20T21:50:31","guid":{"rendered":"https:\/\/icardio.ca\/episode-21-akira-endo-the-discovery-of-statins\/"},"modified":"2026-05-21T16:42:33","modified_gmt":"2026-05-21T20:42:33","slug":"episode-21-akira-endo-the-discovery-of-statins","status":"publish","type":"post","link":"https:\/\/icardio.ca\/en\/episode-21-akira-endo-the-discovery-of-statins\/","title":{"rendered":"Episode 21 &#8211; Akira Endo: The Discovery of Statins"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"17857\" class=\"elementor elementor-17857 elementor-17845\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fb9dedb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fb9dedb\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-088fd76\" data-id=\"088fd76\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-26379fa elementor-widget elementor-widget-heading\" data-id=\"26379fa\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Episode 21 &#8211; Akira Endo: The Discovery of Statins<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1dd6986 elementor-align-center elementor-widget elementor-widget-post-info\" data-id=\"1dd6986\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-6610920 elementor-inline-item\" itemprop=\"author\">\n\t\t\t\t\t\t<a href=\"https:\/\/icardio.ca\/en\/author\/icardio\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-author\">\n\t\t\t\t\t\t\t<span class=\"elementor-post-info__item-prefix\">\u00c9crit par<\/span>\n\t\t\t\t\t\t\t\t\t\ticardio\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-a890a19 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/icardio.ca\/en\/2026\/05\/20\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t<span class=\"elementor-post-info__item-prefix\">Publi\u00e9 le <\/span>\n\t\t\t\t\t\t\t\t\t\t<time>20 May 2026<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4cc21ce elementor-widget elementor-widget-elementskit-breadcrumb\" data-id=\"4cc21ce\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"elementskit-breadcrumb.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"ekit-wid-con\" ><ol class=\"ekit-breadcrumb\"><li class=\"ekit_breadcrumbs_start\"><a href=\"https:\/\/icardio.ca\/en\/\">Home<\/a><\/li> <li class=\"brd_sep\"> &raquo; <\/li> <li><a href=\"https:\/\/icardio.ca\/en\/category\/history-of-cardiology\/\">History of cardiology<\/a><\/li> <li class=\"brd_sep\"> &raquo; <\/li>  <li>Episode 21 &#8211; Akira Endo: The Discovery of Statins<\/li><\/ol><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d446bdb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d446bdb\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-54eda83\" data-id=\"54eda83\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2caa6b47 elementor-widget elementor-widget-theme-post-featured-image elementor-widget-image\" data-id=\"2caa6b47\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"theme-post-featured-image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1402\" height=\"1122\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1.png\" class=\"attachment-full size-full wp-image-17858\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1.png 1402w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1-300x240.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1-1024x819.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1-768x615.png 768w\" sizes=\"(max-width: 1402px) 100vw, 1402px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fd5f77f e-flex e-con-boxed e-con e-parent\" data-id=\"fd5f77f\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9a943bc e-flex e-con-boxed e-con e-child\" data-id=\"9a943bc\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f6c247e elementor-widget elementor-widget-text-editor\" data-id=\"f6c247e\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>responsible for the obstruction of coronary arteries and that its rupture could trigger a heart attack.<\/p><p>At that time, <strong>two major therapeutic approaches<\/strong> emerged.<br \/>The first consisted of compressing the obstruction in order to reopen the artery, while the second aimed to bypass the diseased area through coronary artery bypass surgery.<\/p><p>Over time, however, it became clear that <strong>these treatments did not cure<\/strong> the disease itself. They mainly relieved symptoms related to arterial blockages, while the atherosclerotic disease remained present. The risk of acute cardiovascular events therefore persisted despite these interventions.<\/p><p>One major question remained unanswered: how could physicians <strong>directly target<\/strong> the cause of the disease itself, namely the development of atherosclerotic plaques?<\/p><p>Gradually, certain observations attracted researchers\u2019 attention.<br \/>In particular, it became apparent that a diet rich in cholesterol seemed to promote the development of disease within the arteries.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b83700d e-flex e-con-boxed e-con e-parent\" data-id=\"b83700d\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-14fca0c e-flex e-con-boxed e-con e-child\" data-id=\"14fca0c\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-51e6e1f elementor-widget elementor-widget-heading\" data-id=\"51e6e1f\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A young researcher fascinated by nature<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-179148f e-flex e-con-boxed e-con e-parent\" data-id=\"179148f\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9a81c8b e-flex e-con-boxed e-con e-child\" data-id=\"9a81c8b\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-27994f0 elementor-widget elementor-widget-text-editor\" data-id=\"27994f0\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>It was in this context that Akira Endo entered the scene.<\/p><p>Born in Japan in November 1933, his interest in science began at a very young age through the influence of his grandfather, who introduced him to the wonders of nature.<\/p><p>One experience in particular left a lasting impression on him.<br \/>Together, they observed a fungus capable of killing flies while remaining harmless to humans.<\/p><p>This discovery would profoundly influence his scientific future and guide him toward a career in biochemistry.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7ed6e5d e-con-full e-flex e-con e-child\" data-id=\"7ed6e5d\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2b150c5 elementor-widget elementor-widget-image\" data-id=\"2b150c5\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"640\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Arika-Endo-1024x819.png\" class=\"attachment-large size-large wp-image-17859\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Arika-Endo-1024x819.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Arika-Endo-300x240.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Arika-Endo-768x615.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Arika-Endo.png 1402w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-272e52d e-flex e-con-boxed e-con e-parent\" data-id=\"272e52d\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8416eed e-flex e-con-boxed e-con e-child\" data-id=\"8416eed\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-66a9ede elementor-widget elementor-widget-text-editor\" data-id=\"66a9ede\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>In Japan, Akira Endo became a biochemist at the chemical company Sankyo in Tokyo.<\/p><p>His early work later allowed him to pursue research for two years at the Albert Einstein Medical College in New York.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a8a16c9 e-flex e-con-boxed e-con e-parent\" data-id=\"a8a16c9\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-a7583fd e-flex e-con-boxed e-con e-child\" data-id=\"a7583fd\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b654a47 elementor-widget elementor-widget-heading\" data-id=\"b654a47\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Searching for a way to block cholesterol<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-af20590 e-flex e-con-boxed e-con e-parent\" data-id=\"af20590\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-1ba6999 e-flex e-con-boxed e-con e-child\" data-id=\"1ba6999\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2efacb9 elementor-widget elementor-widget-text-editor\" data-id=\"2efacb9\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Endo\u2019s research focused mainly on <strong>lipid metabolism<\/strong> \u2014 in other words, fats.<\/p><p>At that time, a true revolution was taking place in cardiac surgery.<br \/>Surgeons began using the left internal mammary artery \u2014 an artery located beneath the chest wall \u2014 for coronary bypass surgery instead of using veins taken from the leg.<\/p><p>This innovation sparked his interest in atherosclerosis.<br \/>He wanted to find a way to block the production of cholesterol.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3f1adbe e-flex e-con-boxed e-con e-parent\" data-id=\"3f1adbe\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-33f7554 e-flex e-con-boxed e-con e-child\" data-id=\"33f7554\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-10d0b1f elementor-widget elementor-widget-text-editor\" data-id=\"10d0b1f\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Researchers already knew that part of the cholesterol circulating in the blood came from food, but that nearly <strong>two thirds were produced by the liver<\/strong>.<br \/>It was therefore on this organ that he concentrated his efforts.<\/p><p>He returned to the idea inspired by the fungus he had observed in childhood.<br \/>His hypothesis was bold: certain natural substances might be capable of blocking cholesterol production.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1c8b418 e-con-full e-flex e-con e-child\" data-id=\"1c8b418\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e705c82 elementor-widget elementor-widget-image\" data-id=\"e705c82\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"451\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2024\/04\/fabrication-foie-1024x577.png\" class=\"attachment-large size-large wp-image-5832\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2024\/04\/fabrication-foie-1024x577.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2024\/04\/fabrication-foie-300x169.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2024\/04\/fabrication-foie-768x433.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2024\/04\/fabrication-foie-1536x866.png 1536w, https:\/\/icardio.ca\/wp-content\/uploads\/2024\/04\/fabrication-foie.png 1570w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f3dd295 e-flex e-con-boxed e-con e-parent\" data-id=\"f3dd295\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-6f7aa5e e-flex e-con-boxed e-con e-child\" data-id=\"6f7aa5e\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f11a18d elementor-widget elementor-widget-heading\" data-id=\"f11a18d\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The discovery of statins<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ae00e39 e-flex e-con-boxed e-con e-parent\" data-id=\"ae00e39\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-eb5428d e-flex e-con-boxed e-con e-child\" data-id=\"eb5428d\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-11d8bd4 elementor-widget elementor-widget-text-editor\" data-id=\"11d8bd4\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Experiments multiplied.<br \/>Thousands of substances were analyzed.<br \/>Failures were numerous, but they fueled his determination.<\/p><p>Then came a major breakthrough.<br \/>He identified a substance belonging to the statin family, a class of medications that would transform the treatment of coronary artery disease.<\/p><p>Ironically, this substance originated from a fungus belonging to the <strong>Penicillium family<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fdabdc2 e-flex e-con-boxed e-con e-parent\" data-id=\"fdabdc2\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-1887ee9 e-flex e-con-boxed e-con e-child\" data-id=\"1887ee9\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-66ea056 elementor-widget elementor-widget-text-editor\" data-id=\"66ea056\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>History presents a fascinating parallel.<br \/>Penicillin, discovered decades earlier, had dramatically reduced deaths caused by infections, which at the time represented the leading cause of mortality.<\/p><p>As infectious diseases declined, coronary artery disease gradually became the leading cause of death in industrialized countries.<\/p><p>Statins would, in turn, profoundly change this reality.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b4e9e8e e-con-full e-flex e-con e-child\" data-id=\"b4e9e8e\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c65375f elementor-widget elementor-widget-image\" data-id=\"c65375f\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"484\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/01\/podium-premiere-1024x620.png\" class=\"attachment-large size-large wp-image-15954\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/01\/podium-premiere-1024x620.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/01\/podium-premiere-300x182.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/01\/podium-premiere-768x465.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/01\/podium-premiere.png 1280w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-60d54fe e-flex e-con-boxed e-con e-parent\" data-id=\"60d54fe\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ae8a0cf e-flex e-con-boxed e-con e-child\" data-id=\"ae8a0cf\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e78a565 elementor-widget elementor-widget-heading\" data-id=\"e78a565\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Mevastatin: a discovery initially overlooked<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0dade88 elementor-widget elementor-widget-text-editor\" data-id=\"0dade88\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>In the 1970s, Endo named his <strong>first molecule \u201cmevastatin.\u201d<\/strong><br \/>This medication lowered LDL cholesterol \u2014 often referred to as \u201cbad cholesterol\u201d \u2014 by 20 to 35%.<\/p><p>The Sankyo company obtained the rights to the discovery in 1974, and the first scientific results were published in 1976.<\/p><p>That same year, Endo presented his work at an international symposium in Philadelphia dedicated to drugs affecting lipid metabolism.<\/p><p>Surprisingly, few participants seemed truly interested in the discovery.<\/p><p>Despite this, he continued his work<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b912967 e-flex e-con-boxed e-con e-parent\" data-id=\"b912967\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-33823c0 e-flex e-con-boxed e-con e-child\" data-id=\"33823c0\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3e09898 elementor-widget elementor-widget-heading\" data-id=\"3e09898\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Remarkable results<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2bd880a elementor-widget elementor-widget-text-editor\" data-id=\"2bd880a\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Not far from the Sankyo laboratories, <strong>Dr. Akira Yamamoto<\/strong> was treating patients with familial hypercholesterolemia, a rare inherited condition causing extremely high cholesterol levels.<\/p><p>He asked Endo to provide him with this new medication.<\/p><p>After adjusting the dosage, the results proved remarkable.<\/p><p>Endo then convinced Sankyo to conduct a clinical study documenting the cholesterol reduction, something that had never before been rigorously demonstrated.<\/p><p>However, the company gradually excluded him from the project before ultimately dismissing him.<br \/>Mevastatin would never be commercialized by Sankyo.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b3016e9 e-con-full e-flex e-con e-child\" data-id=\"b3016e9\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-376705e elementor-widget elementor-widget-image\" data-id=\"376705e\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"640\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Dr-Akira-Yamamoto-1024x819.png\" class=\"attachment-large size-large wp-image-17860\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Dr-Akira-Yamamoto-1024x819.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Dr-Akira-Yamamoto-300x240.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Dr-Akira-Yamamoto-768x615.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Dr-Akira-Yamamoto.png 1402w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f4bd578 e-flex e-con-boxed e-con e-parent\" data-id=\"f4bd578\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8bf5fdd e-flex e-con-boxed e-con e-child\" data-id=\"8bf5fdd\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-81de7af elementor-widget elementor-widget-heading\" data-id=\"81de7af\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The arrival of Merck<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8454c5 elementor-widget elementor-widget-text-editor\" data-id=\"c8454c5\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The story could have ended there.<\/p><p>However, an American scientist named Roy Vagelos, recently appointed president of the pharmaceutical company Merck, became very interested in Endo\u2019s work.<\/p><p>Familiar with the mechanisms involved in cholesterol production by the liver, he quickly understood the tremendous potential of this discovery.<\/p><p>An agreement was eventually signed between Sankyo and Merck.<br \/>The document reportedly consisted of only a single page.<\/p><p>Merck obtained the scientific data and the rights to future statin-related research, although mevastatin itself remained the property of Sankyo.<\/p><p>Endo later contributed to the development of <strong>a related product: lovastatin<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-196a16b e-flex e-con-boxed e-con e-parent\" data-id=\"196a16b\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-4e4d9c3 e-flex e-con-boxed e-con e-child\" data-id=\"4e4d9c3\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eaa2a75 elementor-widget elementor-widget-heading\" data-id=\"eaa2a75\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A revolution in cardiology<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7cacacb elementor-widget elementor-widget-text-editor\" data-id=\"7cacacb\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Merck subsequently continued the development of several other statins.<\/p><p>In 1994, nearly 18 years after Endo\u2019s initial presentation in Philadelphia, an important Scandinavian study was published: <strong>the Scandinavian Simvastatin Survival Study<\/strong>, better known as the 4S study.<\/p><p>This study demonstrated that lowering cholesterol by approximately 35% in patients with coronary artery disease could significantly reduce heart attacks and cardiovascular mortality.<\/p><p>The publication permanently transformed modern cardiology.<\/p><p>Statins became one of the most important therapies in cardiovascular prevention.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d4f3058 e-con-full e-flex e-con e-child\" data-id=\"d4f3058\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4797bdd elementor-widget elementor-widget-image\" data-id=\"4797bdd\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"640\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Etude-4S-1024x819.png\" class=\"attachment-large size-large wp-image-17861\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Etude-4S-1024x819.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Etude-4S-300x240.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Etude-4S-768x615.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Etude-4S.png 1402w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-460e3e2 e-flex e-con-boxed e-con e-parent\" data-id=\"460e3e2\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9a72a0e e-flex e-con-boxed e-con e-child\" data-id=\"9a72a0e\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f92f0d4 elementor-widget elementor-widget-heading\" data-id=\"f92f0d4\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Recognition at last<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-66470a1 elementor-widget elementor-widget-text-editor\" data-id=\"66470a1\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>As a small anecdote, in 1994 Endo visited his physician and learned that his own cholesterol level was elevated.<br \/>His doctor then reassured him by explaining that an excellent treatment for this problem now existed.<\/p><p>Over the years, Akira Endo received numerous scientific honors.<\/p><p>In 2008, he was awarded the prestigious Lasker-DeBakey Clinical Medical Research Award for his lifetime achievements.<\/p><p>Several recipients of this award later went on to receive the Nobel Prize.<\/p><p>History will remember that a researcher fascinated by fungi helped transform the treatment of cardiovascular disease throughout the world.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-c59d2a6\" data-id=\"c59d2a6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5ec5735 elementor-search-form--skin-classic elementor-search-form--button-type-icon elementor-search-form--icon-search elementor-widget elementor-widget-global elementor-global-6511 elementor-global-3416 elementor-widget-search-form\" data-id=\"5ec5735\" data-element_type=\"widget\" data-settings=\"{&quot;skin&quot;:&quot;classic&quot;,&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"search-form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<search role=\"search\">\n\t\t\t<form class=\"elementor-search-form\" action=\"https:\/\/icardio.ca\/en\/\" method=\"get\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-search-form__container\">\n\t\t\t\t\t<label class=\"elementor-screen-only\" for=\"elementor-search-form-5ec5735\">Search<\/label>\n\n\t\t\t\t\t\n\t\t\t\t\t<input id=\"elementor-search-form-5ec5735\" placeholder=\"Search...\" class=\"elementor-search-form__input\" type=\"search\" name=\"s\" value=\"\">\n\t\t\t\t\t<input type='hidden' name='lang' value='en' \/>\n\t\t\t\t\t\t\t\t\t\t\t<button class=\"elementor-search-form__submit\" type=\"submit\" aria-label=\"Search\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"e-font-icon-svg-container\"><svg class=\"fa fa-search e-font-icon-svg e-fas-search\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M505 442.7L405.3 343c-4.5-4.5-10.6-7-17-7H372c27.6-35.3 44-79.7 44-128C416 93.1 322.9 0 208 0S0 93.1 0 208s93.1 208 208 208c48.3 0 92.7-16.4 128-44v16.3c0 6.4 2.5 12.5 7 17l99.7 99.7c9.4 9.4 24.6 9.4 33.9 0l28.3-28.3c9.4-9.4 9.4-24.6.1-34zM208 336c-70.7 0-128-57.2-128-128 0-70.7 57.2-128 128-128 70.7 0 128 57.2 128 128 0 70.7-57.2 128-128 128z\"><\/path><\/svg><\/div>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/button>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t<\/search>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-515dff8d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"515dff8d\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-72235494\" data-id=\"72235494\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-81fce3d elementor-widget elementor-widget-global elementor-global-6517 elementor-global-3406 elementor-widget-heading\" data-id=\"81fce3d\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Share this article<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-12eded0 e-flex e-con-boxed e-con e-parent\" data-id=\"12eded0\" data-element_type=\"container\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-199f7ba uael-share-buttons--view-text elementor-share-buttons--align-center uael-stylex-inline elementor-grid-0 elementor-widget elementor-widget-global elementor-global-6519 elementor-global-3396 elementor-widget-uael-social-share\" data-id=\"199f7ba\" data-element_type=\"widget\" data-settings=\"{&quot;alignment&quot;:&quot;center&quot;,&quot;row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:15,&quot;sizes&quot;:[]},&quot;button_size&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0.75,&quot;sizes&quot;:[]},&quot;button_height&quot;:{&quot;unit&quot;:&quot;em&quot;,&quot;size&quot;:5,&quot;sizes&quot;:[]},&quot;columns&quot;:&quot;0&quot;,&quot;column_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;column_gap_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;column_gap_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;column_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;column_gap_mobile_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;column_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;row_gap_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;row_gap_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0,&quot;sizes&quot;:[]},&quot;row_gap_mobile_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;button_size_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_size_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_size_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_size_mobile_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_size_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_height_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_height_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_height_tablet&quot;:{&quot;unit&quot;:&quot;em&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_height_mobile_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;button_height_mobile&quot;:{&quot;unit&quot;:&quot;em&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;border_size&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:2,&quot;sizes&quot;:[]},&quot;border_size_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;border_size_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;border_size_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;border_size_mobile_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;border_size_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"uael-social-share.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"uael-style-inline uael-container uael-floating-align-\" data-pin_data_url=\"\" data-share_url_type=\"current_page\" data-share_url=\"\">\n\t\t\t<div class=\"elementor-grid uael-floating-align-\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-grid-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a  class=\"uael-share-btn-facebook\">\n\t\t\t\t\t\t\t<div class=\"uael-share-btn elementor-animation-pulse uaelbtn-shape-circle uaelbtn--skin-boxed\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-share-btn__text\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-share-btn__title\">\n\t\t\t\t\t\t\t\t\t\t\t\tFacebook\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-grid-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a  class=\"uael-share-btn-twitter\">\n\t\t\t\t\t\t\t<div class=\"uael-share-btn elementor-animation-pulse uaelbtn-shape-circle uaelbtn--skin-boxed\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-share-btn__text\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-share-btn__title\">\n\t\t\t\t\t\t\t\t\t\t\t\tTwitter\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-grid-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a  class=\"uael-share-btn-linkedin\">\n\t\t\t\t\t\t\t<div class=\"uael-share-btn elementor-animation-pulse uaelbtn-shape-circle uaelbtn--skin-boxed\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-share-btn__text\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-share-btn__title\">\n\t\t\t\t\t\t\t\t\t\t\t\tLinkedin\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-grid-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a  class=\"uael-share-btn-whatsapp\">\n\t\t\t\t\t\t\t<div class=\"uael-share-btn elementor-animation-pulse uaelbtn-shape-circle uaelbtn--skin-boxed\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-share-btn__text\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-share-btn__title\">\n\t\t\t\t\t\t\t\t\t\t\t\tWhatsapp\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-grid-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a  class=\"uael-share-btn-email\">\n\t\t\t\t\t\t\t<div class=\"uael-share-btn elementor-animation-pulse uaelbtn-shape-circle uaelbtn--skin-boxed\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-share-btn__text\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-share-btn__title\">\n\t\t\t\t\t\t\t\t\t\t\t\tEmail\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-grid-item\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a  class=\"uael-share-btn-print\">\n\t\t\t\t\t\t\t<div class=\"uael-share-btn elementor-animation-pulse uaelbtn-shape-circle uaelbtn--skin-boxed\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"uael-share-btn__text\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-share-btn__title\">\n\t\t\t\t\t\t\t\t\t\t\t\tPrint\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a28e6b8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a28e6b8\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-44961b4\" data-id=\"44961b4\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a4c1be8 elementor-widget elementor-widget-global elementor-global-6513 elementor-global-3413 elementor-widget-heading\" data-id=\"a4c1be8\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Related articles<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8720d47 elementor-grid-1 elementor-posts--thumbnail-left elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-global elementor-global-6521 elementor-global-3422 elementor-widget-posts\" data-id=\"8720d47\" data-element_type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:20,&quot;sizes&quot;:[]},&quot;classic_columns_tablet&quot;:&quot;2&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\" role=\"list\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-8770 post type-post status-publish format-standard has-post-thumbnail hentry category-general-en category-prevention-en tag-articles-mis-de-lavant-en tag-articles-mis-de-lavant-2 tag-articles-mis-de-lavant-en-3\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/healthy-habits-for-a-healthy-heart-cardiovascular-exercise-and-a-healthy-weight\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"169\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2024\/08\/Coeur-fruits-300x169.jpg\" class=\"attachment-medium size-medium wp-image-8771\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2024\/08\/Coeur-fruits-300x169.jpg 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2024\/08\/Coeur-fruits-1024x575.jpg 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2024\/08\/Coeur-fruits-768x431.jpg 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2024\/08\/Coeur-fruits.jpg 1280w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/healthy-habits-for-a-healthy-heart-cardiovascular-exercise-and-a-healthy-weight\/\" >\n\t\t\t\tHealthy Habits for a Healthy Heart<br>&#8211; Cardiovascular Exercise and a Healthy Weight\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t28\/08\/2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/healthy-habits-for-a-healthy-heart-cardiovascular-exercise-and-a-healthy-weight\/\" aria-label=\"Read more about Healthy Habits for a Healthy Heart&lt;br&gt;&#8211; Cardiovascular Exercise and a Healthy Weight\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-15950 post type-post status-publish format-standard has-post-thumbnail hentry category-coronary-heart-diseases category-general-en category-valvular-cardiovascular-diseases tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/diabetes-and-cardiovascular-complications-medical-point-of-view\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"200\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2025\/04\/diabete-sucre-300x200.jpg\" class=\"attachment-medium size-medium wp-image-12389\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2025\/04\/diabete-sucre-300x200.jpg 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/04\/diabete-sucre-1024x683.jpg 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/04\/diabete-sucre-768x512.jpg 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/04\/diabete-sucre-1536x1024.jpg 1536w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/04\/diabete-sucre.jpg 1920w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/diabetes-and-cardiovascular-complications-medical-point-of-view\/\" >\n\t\t\t\tDiabetes and Cardiovascular Complications &#8211; Medical Point of View\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t07\/01\/2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/diabetes-and-cardiovascular-complications-medical-point-of-view\/\" aria-label=\"Read more about Diabetes and Cardiovascular Complications &#8211; Medical Point of View\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-10865 post type-post status-publish format-standard has-post-thumbnail hentry category-general-en category-how-it-works tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/development-of-the-cardiovascular-system\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2025\/01\/coeur-embryo2-300x300.png\" class=\"attachment-medium size-medium wp-image-10876\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2025\/01\/coeur-embryo2-300x300.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/01\/coeur-embryo2-1024x1024.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/01\/coeur-embryo2-150x150.png 150w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/01\/coeur-embryo2-768x768.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2025\/01\/coeur-embryo2.png 1280w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/development-of-the-cardiovascular-system\/\" >\n\t\t\t\tDevelopment of the Cardiovascular System\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t15\/01\/2025\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/development-of-the-cardiovascular-system\/\" aria-label=\"Read more about Development of the Cardiovascular System\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-246972f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"246972f\" data-element_type=\"section\" data-settings=\"{&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-94a8515\" data-id=\"94a8515\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-43a10fe elementor-widget elementor-widget-global elementor-global-6515 elementor-global-3410 elementor-widget-heading\" data-id=\"43a10fe\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Latest articles<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0844166 elementor-grid-1 elementor-posts--thumbnail-left elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-global elementor-global-6523 elementor-global-3419 elementor-widget-posts\" data-id=\"0844166\" data-element_type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:20,&quot;sizes&quot;:[]},&quot;classic_columns_tablet&quot;:&quot;2&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\" role=\"list\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-17857 post type-post status-publish format-standard has-post-thumbnail hentry category-history-of-cardiology tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/episode-21-akira-endo-the-discovery-of-statins\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1-300x240.png\" class=\"attachment-medium size-medium wp-image-17858\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1-300x240.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1-1024x819.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1-768x615.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-livre-statines-1.png 1402w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/episode-21-akira-endo-the-discovery-of-statins\/\" >\n\t\t\t\tEpisode 21 &#8211; Akira Endo: The Discovery of Statins\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t20\/05\/2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/episode-21-akira-endo-the-discovery-of-statins\/\" aria-label=\"Read more about Episode 21 &#8211; Akira Endo: The Discovery of Statins\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-17813 post type-post status-publish format-standard has-post-thumbnail hentry category-valvular-cardiovascular-diseases tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/mitraclip\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-clip-300x240.png\" class=\"attachment-medium size-medium wp-image-17814\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-clip-300x240.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-clip-1024x819.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-clip-768x615.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-clip.png 1402w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/mitraclip\/\" >\n\t\t\t\tMitraClip\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t19\/05\/2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/mitraclip\/\" aria-label=\"Read more about MitraClip\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-17777 post type-post status-publish format-standard has-post-thumbnail hentry category-history-of-cardiology tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/episode-20-dr-russell-ross-the-dynamic-nature-of-atherosclerotic-plaque\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/livre-coeur-cicatrice-300x240.png\" class=\"attachment-medium size-medium wp-image-17778\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/livre-coeur-cicatrice-300x240.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/livre-coeur-cicatrice-1024x819.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/livre-coeur-cicatrice-768x615.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/livre-coeur-cicatrice.png 1402w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/episode-20-dr-russell-ross-the-dynamic-nature-of-atherosclerotic-plaque\/\" >\n\t\t\t\tEpisode 20 &#8211; Dr. Russell Ross: The Dynamic Nature of Atherosclerotic Plaque\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t19\/05\/2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/episode-20-dr-russell-ross-the-dynamic-nature-of-atherosclerotic-plaque\/\" aria-label=\"Read more about Episode 20 &#8211; Dr. Russell Ross: The Dynamic Nature of Atherosclerotic Plaque\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-17733 post type-post status-publish format-standard has-post-thumbnail hentry category-coronary-heart-diseases category-valvular-cardiovascular-diseases tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/understanding-the-unpredictable\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"169\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-craque-fissure-300x169.png\" class=\"attachment-medium size-medium wp-image-17734\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-craque-fissure-300x169.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-craque-fissure-1024x576.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-craque-fissure-768x432.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-craque-fissure-1536x864.png 1536w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/Coeur-craque-fissure.png 1672w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/understanding-the-unpredictable\/\" >\n\t\t\t\tUnderstanding the Unpredictable\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t17\/05\/2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/understanding-the-unpredictable\/\" aria-label=\"Read more about Understanding the Unpredictable\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-17604 post type-post status-publish format-standard has-post-thumbnail hentry category-exams tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/stress-cardiac-magnetic-resonance-imaging-cardiac-mri\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"200\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-plage-aimant-1-300x200.png\" class=\"attachment-medium size-medium wp-image-17605\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-plage-aimant-1-300x200.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-plage-aimant-1-1024x683.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-plage-aimant-1-768x512.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-plage-aimant-1.png 1536w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/stress-cardiac-magnetic-resonance-imaging-cardiac-mri\/\" >\n\t\t\t\tStress Cardiac Magnetic Resonance Imaging (Cardiac MRI)\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t03\/05\/2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/stress-cardiac-magnetic-resonance-imaging-cardiac-mri\/\" aria-label=\"Read more about Stress Cardiac Magnetic Resonance Imaging (Cardiac MRI)\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-17558 post type-post status-publish format-standard has-post-thumbnail hentry category-exams tag-articles-mis-de-lavant-en\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/icardio.ca\/en\/resting-cardiac-magnetic-resonance-imaging-cardiac-mri\/\" tabindex=\"-1\" >\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"200\" src=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-aimant-eau-300x200.png\" class=\"attachment-medium size-medium wp-image-17560\" alt=\"\" srcset=\"https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-aimant-eau-300x200.png 300w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-aimant-eau-1024x683.png 1024w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-aimant-eau-768x512.png 768w, https:\/\/icardio.ca\/wp-content\/uploads\/2026\/05\/coeur-aimant-eau.png 1536w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/icardio.ca\/en\/resting-cardiac-magnetic-resonance-imaging-cardiac-mri\/\" >\n\t\t\t\tResting Cardiac Magnetic Resonance Imaging (Cardiac MRI)\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t02\/05\/2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\n\t\t<a class=\"elementor-post__read-more\" href=\"https:\/\/icardio.ca\/en\/resting-cardiac-magnetic-resonance-imaging-cardiac-mri\/\" aria-label=\"Read more about Resting Cardiac Magnetic Resonance Imaging (Cardiac MRI)\" tabindex=\"-1\" >\n\t\t\tRead more \u00bb\t\t<\/a>\n\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Akira Endo is the Japanese biochemist behind the discovery of statins, a class of medications that transformed the prevention of cardiovascular disease. This article retraces the story of his research, the development of the first statins, and their major impact on reducing heart attacks and cardiovascular mortality. <\/p>\n","protected":false},"author":4,"featured_media":17858,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50],"tags":[65],"class_list":["post-17857","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-history-of-cardiology","tag-articles-mis-de-lavant-en"],"_links":{"self":[{"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/posts\/17857","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/comments?post=17857"}],"version-history":[{"count":6,"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/posts\/17857\/revisions"}],"predecessor-version":[{"id":17878,"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/posts\/17857\/revisions\/17878"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/media\/17858"}],"wp:attachment":[{"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/media?parent=17857"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/categories?post=17857"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/icardio.ca\/en\/wp-json\/wp\/v2\/tags?post=17857"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}